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ForumsMarketplace & Listings[VERIFIED] Vendor application thread — apply here Page 14

[VERIFIED] Vendor application thread — apply here

mike_mod Mon, Feb 5, 2024 at 8:00 PM 279 replies 37,725 viewsPage 14 of 20
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Mar 24, 2024 at 8:19 PM#66

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Carry on.

35 8PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 32 others
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james_edin
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Mar 25, 2024 at 4:26 PM#67

Found this through search years later and it is still the best discussion of the question, so adding one thing. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

36 9Dr.PathRoch, mona_PHX, andrew_nyc and 33 others
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MaxMetOK
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Mar 26, 2024 at 12:32 PM#68
PharmacoVig_BOS said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

37 10DoseLogDan, SleepFixSam, PurityPaulOR and 34 others
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stefan_berlin
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Mar 27, 2024 at 8:38 AM#69
PharmacoVig_BOS said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Bookmarking. The distinction being drawn above is the one nobody else makes. I will report back once I have actually tried it.

38 11TirzTom, TrialTracker_MD, JennaRN and 35 others
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TrialTracker_MD
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Mar 28, 2024 at 4:43 AM#70

Adding the clinical framing, because it changes how the question reads. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

10 8lori_vegas, Dr.PulmRoch, maya_sedona and 7 others
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