BethLabQueen said:Practical: whatever you change, write down the date and the reason.
Thank you for spelling out the reasoning rather than just the conclusion. Sending this to two other people who asked me the same thing last week.
Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Dr.PathRoch said:The mechanism and the magnitude are separate questions.
Same pattern here, and in the same order. The detail I would add is minor and it is already implied above.
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Browse GL BiochemClosing the loop on my own question.
Closing the loop. The answer turned out to depend on the detail I had left out of the opening post, which is a lesson about how to ask rather than about the subject.
Adding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.