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ForumsDosing & ProtocolsTirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide Page 6

Tirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide

Dr.Martinez Mon, Feb 19, 2024 at 5:20 PM 181 replies 34,127 viewsPage 6 of 20
Dr.EndoEP
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Mar 10, 2024 at 6:43 AM#26

From the other side of the consultation, briefly. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

Last edited: Mar 10, 2024 at 8:43 AM
3 3NicoleRaleigh, james_edin, FranDenver
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LabKate
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Mar 12, 2024 at 11:11 AM#27
Dr.EndoEP said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Same pattern here, and in the same order.

2 2laura_annarbor, JenMemphis
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A1cHero_PHX
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Mar 14, 2024 at 3:38 PM#28
Dr.EndoEP said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Adding the part of the answer the thread has not reached. The trials generally allowed a step to be held or reduced and then retried, and people who did that mostly arrived at the same place a few weeks later. The end point of the ladder is set by tolerability, not by a schedule, and there is no evidence that reaching the top faster produces a better outcome.

That is the short version; the long version is somebody else's post.

1 1tampaLisa73
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quinn_sf
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Mar 16, 2024 at 8:04 PM#29

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

50 0andrew_nyc, Dr.EndoEP, GraceAZ_72 and 47 others
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Dr.Martinez
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Mar 19, 2024 at 12:28 AM#30

Closing the loop on my own question.

Update — I came back down one step, held for a month, then went up again and it was uneventful the second time. Same ladder, slower.

Last edited: Mar 19, 2024 at 5:28 AM
28 3adam_van, Dr.SurgeonPGH, rachel_ABQ and 25 others
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