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ForumsExercise & Body CompositionPilates for core strength during GLP-1 weight loss — what worked for you? Page 4

Pilates for core strength during GLP-1 weight loss — what worked for you?

Dr.RheumBOS Sat, Apr 26, 2025 at 9:14 AM 35 replies 1,945 viewsPage 4 of 7
Dr.MetabolicMD
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May 9, 2025 at 5:55 AM#16

Adding the clinical framing, because it changes how the question reads.

Physical therapist weighing in on lean mass. I work with bariatric and metabolic patients daily.

The resistance training evidence is critical here:

The Lundgren 2024 JAMA paper[1] showed that structured resistance training preserved 73% more lean mass in GLP-1 patients vs medication alone. When discussing lean mass, we MUST include the exercise component.

My minimum prescription: 3x/week compound movements (squat, deadlift, press, row), progressive overload, 7-10K steps/day, and 1.2-1.6g protein/kg/day.

References:
[1] Lundgren JR, et al. JAMA. 2024;331(1):38-48.
Last edited: May 9, 2025 at 7:55 AM
6 4SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 3 others
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nick_SD_fit
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May 11, 2025 at 7:14 AM#17
anders_CPH said:
Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the…

Saving this. It is the first explanation that did not require me to already understand it. I will report back once I have actually tried it.

Last edited: May 11, 2025 at 9:14 AM
7 5Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 4 others
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hans_munich
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May 13, 2025 at 8:32 AM#18

Adding the clinical framing, because it changes how the question reads.

My endo's protocol for lean mass plateau: if weight loss stalls for 6+ weeks at current dose, we go through this checklist before titrating up:

  1. Food diary review — is intake creeping up?
  2. Protein check — minimum 100g/day
  3. Activity audit — steps + resistance training
  4. Sleep quality — poor sleep kills GLP-1 efficacy
  5. Stress/cortisol management

Only after addressing all of these do we increase the dose. Often fixing one lifestyle factor restarts progress without needing more medication.

8 6Dr.LipidDallas, alex_tucson, kevin_tulsa and 5 others
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adam_van
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May 15, 2025 at 9:49 AM#19
hans_munich said:
My endo's protocol for lean mass plateau: if weight loss stalls for 6+ weeks at current dose, we go through this checklist before titrating up: Food…

This matches mine closely enough to be worth saying so out loud. Posting only so the count is not one.

9 7tommy_boulder, hyun_seoul, jim_asheville and 6 others
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Admin
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May 17, 2025 at 11:05 AM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Report rather than reply if it drifts again.

Last edited: May 17, 2025 at 3:05 PM
31 4PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 28 others
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