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ForumsMASH / Liver DiseaseMASH resolution without worsening fibrosis — looking for input Page 4

MASH resolution without worsening fibrosis — looking for input

PeptideSynthNJ Wed, Jul 2, 2025 at 8:50 AM 40 replies 1,673 viewsPage 4 of 8
greg_boulder
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Jul 16, 2025 at 1:42 AM#16
Dr.EndoIndy said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Mine went the same way, slower.

Last edited: Jul 16, 2025 at 3:42 AM
42 15denise_HTX, raj_cambridge, ingrid_STO and 39 others
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wendy_avl
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Jul 17, 2025 at 3:20 PM#17

One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Last edited: Jul 17, 2025 at 9:20 PM
43 16DoseLogDan, SleepFixSam, PurityPaulOR and 40 others
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TrialTracker_MD
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Jul 19, 2025 at 4:58 AM#18

Following on from PharmacoVig_BOS — and this may be the naive question:

What would you measure differently if you were starting again?

44 17maya_sedona, stefan_berlin, Dr.EM_Chicago and 41 others
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oliver_london
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Jul 20, 2025 at 6:35 PM#19
wendy_avl said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

45 18jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 42 others
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Admin
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Jul 22, 2025 at 8:11 AM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.

17 15PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 14 others
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