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ForumsMASH / Liver DiseaseMASH resolution without worsening fibrosis — looking for input Page 3

MASH resolution without worsening fibrosis — looking for input

PeptideSynthNJ Wed, Jul 2, 2025 at 8:50 AM 40 replies 1,673 viewsPage 3 of 8
marco_milano
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Jul 8, 2025 at 5:18 AM#11
LindaRN_retired said:
Liver imaging follow-up for liver and MASH: FibroScan at baseline showed CAP score 313 dB/m (moderate steatosis) and stiffness 9.8 kPa (possible…

Saving this. It is the first explanation that did not require me to already understand it.

Last edited: Jul 8, 2025 at 9:18 AM
37 10kevin_tulsa, Dr.PainCLE, mike_mealprep and 34 others
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Dr.EndoIndy
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Indianapolis, IN
Jul 9, 2025 at 7:00 PM#12

Adding the clinical framing, because it changes how the question reads. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

38 11LeilaHI, marcus_mpls, DeniseRN_TPA and 35 others
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PharmD_Rodriguez
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Miami, FL
Jul 11, 2025 at 8:42 AM#13
BariatricNurseD said:
Liver enzyme update related to liver and MASH: I had mildly elevated ALT/AST at baseline (likely NAFLD).

This is where I part company with the consensus forming above. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

39 12robert_kc, dan_philly, MeganSA_TX and 36 others
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PharmacoVig_BOS
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Jul 12, 2025 at 10:23 PM#14

Adding the numbers, since they settle part of this. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

40 13kate.chem, DataDave, Dr.GutHealth and 37 others
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mike_mod
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Jul 14, 2025 at 12:03 PM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Thread quality here is what the rules are for. Keep it up.

41 14PurityPaulOR, MaxMetOK, MounjBrad and 38 others
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