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ForumsLab Results & BiomarkersSHBG changes during weight loss on GLP-1 — my results so far Page 8

SHBG changes during weight loss on GLP-1 — my results so far

tampaLisa73 Thu, Sep 18, 2025 at 7:38 AM 45 replies 1,803 viewsPage 8 of 9
JessicaM_2024
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Feb 14, 2026 at 12:49 PM#36

A narrower follow-up, since the general answer is now clear:

What did you change at the same time, and can you separate the two now?

Last edited: Feb 14, 2026 at 1:49 PM
22 20james_edin, FranDenver, Dr.BariatricHTX and 19 others
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NicoleRaleigh
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Feb 22, 2026 at 11:09 PM#37
hank_denver said:
Say what you would expect to see if you were wrong, before you look.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

Last edited: Feb 23, 2026 at 12:09 AM
23 21MikeFit_NJ, InsuranceTom, WendyG_ATL and 20 others
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Dr.RheumBOS
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Mar 3, 2026 at 9:24 AM#38
hank_denver said:
Say what you would expect to see if you were wrong, before you look.

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

Last edited: Mar 3, 2026 at 3:24 PM
24 22cory_ATX, lori_vegas, Dr.PulmRoch and 21 others
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HealthEcon_DC
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Mar 11, 2026 at 7:34 PM#39
hank_denver said:
Say what you would expect to see if you were wrong, before you look.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. I will report back once I have actually tried it.

25 23TirzTom, TrialTracker_MD, JennaRN and 22 others
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andrew_nyc
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Mar 20, 2026 at 5:39 AM#40

Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Ask again with the specifics and you will get a better answer than this one.

47 20JessicaM_2024, TomFromTexas, mike.trainer_LA and 44 others
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