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ForumsLab Results & BiomarkersSHBG changes during weight loss on GLP-1 — my results so far Page 6

SHBG changes during weight loss on GLP-1 — my results so far

tampaLisa73 Thu, Sep 18, 2025 at 7:38 AM 45 replies 1,803 viewsPage 6 of 9
B12Beth
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Nov 21, 2025 at 6:06 PM#26
VanRx_Mike said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Adding the part of the answer the thread has not reached. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

41 14GraceAZ_72, carl_compliance, DanielChem_CHI and 38 others
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Dr.PulmRoch
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Nov 30, 2025 at 6:58 AM#27

One concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

42 15traveltech_sara, AttorneyGrant, DebRD_ATL and 39 others
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mia_MS2
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Dec 8, 2025 at 7:45 PM#28

Following on from VanRx_Mike — and this may be the naive question:

How would you tell the difference between that and the alternative explanation?

43 16dave_SLC, FDA_TrackerJim, ricardo_MIA and 40 others
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MikeNYC_runner
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Dec 17, 2025 at 8:28 AM#29
Dr.PulmRoch said:
Keep the original post as written when you update it, and add the correction underneath.

This is where I part company with the consensus forming above. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

Last edited: Dec 17, 2025 at 10:28 AM
44 17GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 41 others
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tampaLisa73
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Dec 25, 2025 at 9:06 PM#30

Closing the loop on my own question.

Late follow-up. I did not do what was suggested, I did something adjacent, and it worked; posting the difference in case it matters to somebody.

16 14TomFromTexas, mike.trainer_LA, sarah_nash92 and 13 others
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