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ForumsRetatrutide & Triple AgonistsWill reta make sema and tirz obsolete? Page 4

Will reta make sema and tirz obsolete?

andrew_nyc Sun, Apr 5, 2026 at 9:23 AM 33 replies 1,028 viewsPage 4 of 7
Dr.RenalNash
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Apr 11, 2026 at 12:24 AM#16

Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Apr 11, 2026 at 5:24 AM
12 10wei_SG, cory_ATX, lori_vegas and 9 others
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JakeSmashed95
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Apr 11, 2026 at 9:41 PM#17
Dr.RenalNash said:
The mechanism and the magnitude are separate questions.

Mine went the same way, slower. I had assumed I was the exception until I read this.

13 11kevin_tulsa, Dr.PainCLE, mike_mealprep and 10 others
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Dr.CardioMD
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Apr 12, 2026 at 6:57 PM#18
Dr.RenalNash said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

That is the short version; the long version is somebody else's post.

14 12tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 11 others
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BiostatsBrad
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Apr 13, 2026 at 4:12 PM#19

The figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Apr 13, 2026 at 5:12 PM
15 13james_edin, FranDenver, Dr.BariatricHTX and 12 others
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mike_mod
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Apr 14, 2026 at 1:27 PM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Carry on.

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