Is there a simple version of how sema vs tirz are different — anyone have experience?

From the other side of the consultation, briefly. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

PharmHunterJen said:

Start from the measurement rather than the conclusion.

This matches mine closely enough to be worth saying so out loud. Nothing to add that would improve it.

PharmHunterJen said:

Start from the measurement rather than the conclusion.

There is a second half to this that has not been said yet. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

The figures, for anyone assembling their own picture. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here.