Steady-state concentrations across dose tiers — anyone have experience?

NurseKim_ATL said:

If two explanations both fit, the useful question is which one predicts something the other does not.

Adding the part of the answer the thread has not reached. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. No action needed from anybody.

Dr.PulmRoch said:

Practical: whatever you change, write down the date and the reason.

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

Dr.PulmRoch said:

Practical: whatever you change, write down the date and the reason.

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.