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ForumsSide Effects & ManagementHypoglycemia risk with concomitant sulfonylurea use — my results so far Page 2

Hypoglycemia risk with concomitant sulfonylurea use — my results so far

mike.trainer_LA Thu, Apr 4, 2024 at 5:38 PM 34 replies 2,155 viewsPage 2 of 7
Dr.AddMedPHL
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Apr 4, 2024 at 10:16 PM#6
BethLabQueen said:
Holding genuinely reduces total burden rather than redistributing it, because the gastric-emptying component adapts.

I dislike how confidently this board tells people to push through. Incidence figures around 20 to 25% at the higher doses are class-typical, but the trials also had a discontinuation column, and "manageable with protocols" is not the same as manageable for everyone.

32 2FitDadDave, RunnerRach, TrialNerd_Beth and 29 others
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raj_cambridge
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Apr 5, 2024 at 12:05 AM#7

One concrete data point for the thread. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

31 1DoseLogDan, SleepFixSam, PurityPaulOR and 28 others
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Dr.PeteFamMed
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Apr 5, 2024 at 1:54 AM#8
Dr.AddMedPHL said:
I dislike how confidently this board tells people to push through.

There is a second half to this that has not been said yet. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

Last edited: Apr 5, 2024 at 2:54 AM
30 0LindaRN_retired, tommy_boulder, hyun_seoul and 27 others
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anna.melb_AU
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Apr 5, 2024 at 3:43 AM#9

A narrower follow-up, since the general answer is now clear:

Whether holding at a lower dose for longer actually reduces total side-effect burden or just spreads it out?

29 24tammy_FL, Dr.LipidDallas, alex_tucson and 26 others
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mike.trainer_LA
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Apr 5, 2024 at 12:25 PM#10

OP back with an update, since a thread like this is useless without one.

Update. It was not the dose, it was that I had stopped drinking anything because drinking made me feel full. Fixing that fixed most of it.

31 4marcus_mpls, DeniseRN_TPA, SandraNC_45 and 28 others
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