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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingHas anyone dealt with are all coas created equal? mine looks different from others i see? Page 4

Has anyone dealt with are all coas created equal? mine looks different from others i see?

DebRD_ATL Sat, Aug 16, 2025 at 3:55 PM 42 replies 1,906 viewsPage 4 of 9
Dr.SurgeonPGH
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Sep 2, 2025 at 3:35 PM#16

Adding the clinical framing, because it changes how the question reads.

Community-verified vendors for certificates of analysis: I maintain a spreadsheet of Janoshik-verified test results submitted by community members. Across 51 submitted tests:

  • 75% tested at ≥98% purity
  • 18% tested at 95-98% purity
  • 7% tested at <95% purity (concerning)

The vendors with consistently high purity results are listed in the Vendor Directory. We update monthly based on new community submissions.

Last edited: Sep 2, 2025 at 6:35 PM
32 5DoseLogDan, SleepFixSam, PurityPaulOR and 29 others
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MariaRD
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Jun 2024
New Mexico
Sep 4, 2025 at 9:25 PM#17
Dr.SurgeonPGH said:
Community-verified vendors for certificates of analysis: I maintain a spreadsheet of Janoshik-verified test results submitted by community members.

Adding a me-too, because a thread of one person's experience is not much use.

Last edited: Sep 4, 2025 at 10:25 PM
33 6anders_CPH, Dr.NutriCornell, pam_stl and 30 others
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Dr.RaviCardio
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Sep 7, 2025 at 3:15 AM#18
Dr.SurgeonPGH said:
Community-verified vendors for certificates of analysis: I maintain a spreadsheet of Janoshik-verified test results submitted by community members.

HPLC results interpretation for certificates of analysis: when you get your Janoshik report back, here's what the numbers mean:

  • Purity %: Should be >97%. Below 95% is concerning.
  • Retention time: Should match reference standard for the peptide
  • Related substances: Degradation products should be <2% total
  • Single impurity: No individual impurity should exceed 1%

My last batch: 99.2% purity, 0.2% total related substances. Clean chromatogram with single sharp peak at expected retention time. Exactly what you want to see.

Last edited: Sep 7, 2025 at 4:15 AM
34 7mark_tokyo, hans_munich, jason_sac26 and 31 others
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Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
BiostatsBrad
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Jul 2024
Durham, NC
Sep 9, 2025 at 9:03 AM#19
Dr.SurgeonPGH said:
Community-verified vendors for certificates of analysis: I maintain a spreadsheet of Janoshik-verified test results submitted by community members.

Third-party testing services for certificates of analysis besides Janoshik:

  • Janoshik: Gold standard for peptide community, ~$138, 10-14 day turnaround
  • Valitech: US-based, ISO 17025 accredited, ~$218
  • Eurofins: Full pharmaceutical testing suite, more expensive but comprehensive
  • ChemTox: Basic identity and purity testing, ~$128

Janoshik is the community standard but any ISO-accredited analytical lab can verify peptide identity and purity. The key is independence — don't rely solely on the vendor's own testing.

35 8james_edin, FranDenver, Dr.BariatricHTX and 32 others
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mike_mod
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Sep 11, 2025 at 2:50 PM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Report rather than reply if it drifts again.

7 5PurityPaulOR, MaxMetOK, MounjBrad and 4 others
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