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ForumsProgress & Lab Results[PREMIUM] DEXA before/after — anyone have experience? Page 4

[PREMIUM] DEXA before/after — anyone have experience?

PeptideSynthNJ Thu, Sep 18, 2025 at 7:59 AM 47 replies 1,788 viewsPage 4 of 10
SleepDoc_PDX
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Sep 24, 2025 at 7:35 PM#16

Adding the clinical framing, because it changes how the question reads.

Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the skeletal muscle fiber type distribution:

  • Decreased Type IIx (glycolytic, fast-twitch) fibers
  • Increased Type I (oxidative, slow-twitch) fibers
  • Improved mitochondrial density and function
  • Enhanced insulin-stimulated glucose uptake per fiber

This "metabolic remodeling" of muscle may contribute to improved insulin sensitivity independent of total lean mass changes. The muscle you keep becomes metabolically better, even if there's less of it[1].

References:
[1] Pirkmajer S, et al. Front Physiol. 2023;14:1123456.
43 16pete_nash, hank_denver, carlos_SATX and 40 others
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Dr.EM_Chicago
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Sep 25, 2025 at 3:49 PM#17
josh_phd_bmore said:
Body composition tracking via bioimpedance on lean mass (InBody scan every 3 months): Metric Baseline Month 3 Month 6 Month 9 Skeletal Muscle (lbs) 69…

DEXA scan update relevant to lean mass:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

BaselineMonth 6Month 12
Total mass278 lbs213 lbs205 lbs
Fat mass108 lbs78 lbs55 lbs
Lean mass161 lbs145 lbs152 lbs
Body fat %39%31%24%

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The lean mass discussion needs to include body comp data, not just scale weight.

44 17matt_MKE, Dr.ReproEndo, lucas_SP_BR and 41 others
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mia_MS2
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Sep 26, 2025 at 12:03 PM#18
josh_phd_bmore said:
Body composition tracking via bioimpedance on lean mass (InBody scan every 3 months): Metric Baseline Month 3 Month 6 Month 9 Skeletal Muscle (lbs) 69…

Bookmarking. The distinction being drawn above is the one nobody else makes.

45 18dave_SLC, FDA_TrackerJim, ricardo_MIA and 42 others
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VanRx_Mike
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Vancouver, CA
Sep 27, 2025 at 8:17 AM#19

From the other side of the consultation, briefly.

OMG yes. lean mass + resistance training is the combo. Can confirm.

Last edited: Sep 27, 2025 at 11:17 AM
46 19Dr.Martinez, mike_mod, SarahChen_PharmD and 43 others
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mike_mod
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Sep 28, 2025 at 4:30 AM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Thread quality here is what the rules are for. Keep it up.

18 16PurityPaulOR, MaxMetOK, MounjBrad and 15 others
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