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ForumsMASH / Liver DiseaseSurvodutide SYNCHRONIZE Phase 3 — November 2025 Page 4

Survodutide SYNCHRONIZE Phase 3 — November 2025

ZaraB_AL Thu, Sep 12, 2024 at 4:18 AM 56 replies 2,243 viewsPage 4 of 12
carl_compliance
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Sep 23, 2024 at 4:22 PM#16

Clinical perspective, offered as context rather than as advice. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

Last edited: Sep 23, 2024 at 7:22 PM
9 7labquiet_amy, emily_PDX, Dr.SleepRoch and 6 others
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tampaLisa73
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Sep 25, 2024 at 7:51 AM#17
Dr.PathRoch said:
Worth stating the units and the reference range whenever you post a number here.

There is a second half to this that has not been said yet. The gap between trial results and real-world results is consistent and it is not fraud. Trial participants get titration by protocol, scheduled contact, free drug and dietetic support; removing that infrastructure costs a few percentage points every time it has been measured. When your own curve sits below the published mean, that is the likeliest explanation before anything about you or your material.

10 8FitDadDave, RunnerRach, TrialNerd_Beth and 7 others
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lucas_SP_BR
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Sep 26, 2024 at 11:19 PM#18

One concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Worth separating that from the trial evidence, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

11 9zoe_NC, Dr.ObesityLA, NurseKim_ATL and 8 others
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hans_munich
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Munich, DE
Sep 28, 2024 at 2:46 PM#19

One thing that is still open after Dr.PathRoch’s answer:

How would you tell the difference between that and the alternative explanation?

Last edited: Sep 28, 2024 at 8:46 PM
12 10tammy_FL, Dr.LipidDallas, alex_tucson and 9 others
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Admin
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Sep 30, 2024 at 6:12 AM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Carry on.

34 7PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 31 others
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