🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseHas anyone dealt with de novo lipogenesis reduction on glp-1? Page 5

Has anyone dealt with de novo lipogenesis reduction on glp-1?

NurseLeah_Nash Tue, Nov 18, 2025 at 1:33 AM 34 replies 1,698 viewsPage 5 of 7
Dr.PulmRoch
Member
456
2,345
Jun 2024
Rochester, MN
Nov 24, 2025 at 3:49 PM#21

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

46 19rachel_ABQ, traveltech_sara, AttorneyGrant and 43 others
Reply Quote Save Share Report
steve_okc
Member
489
2,123
Jul 2024
Oklahoma City, OK
Nov 25, 2025 at 12:23 AM#22

One thing that is still open after PharmD_Rodriguez’s answer:

How long did you give it before you decided it was working?

Last edited: Nov 25, 2025 at 4:23 AM
47 20JakeSmashed95, NauseaFreeNow, SteveThurs and 44 others
Reply Quote Save Share Report
tammy_FL
Member
234
890
Nov 2024
Tampa, FL
Nov 25, 2025 at 8:57 AM#23
Dr.PulmRoch said:
Say what you would expect to see if you were wrong, before you look.

Pushing back on Dr.PulmRoch here. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

Last edited: Nov 25, 2025 at 2:57 PM
48 21kevin_tulsa, Dr.PainCLE, mike_mealprep and 45 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
Dr.DermMIA
Member
456
2,123
May 2024
Miami, FL
Nov 25, 2025 at 5:31 PM#24
Dr.PulmRoch said:
Say what you would expect to see if you were wrong, before you look.

No disagreement with Dr.PulmRoch. One condition attached. Yes, and the corollary is less popular: if the reasoning holds, it also holds where it produces an answer we do not like.

Last edited: Nov 25, 2025 at 7:31 PM
49 22PeptideChemSF, A1cHero_PHX, Dr.RenalNash and 46 others
Reply Quote Save Share Report
JakeSmashed95
Member
412
1,890
Aug 2024
Arkansas
Online
Nov 26, 2025 at 2:05 AM#25
Dr.PulmRoch said:
Say what you would expect to see if you were wrong, before you look.

Saving this. It is the first explanation that did not require me to already understand it.

50 23tammy_FL, Dr.LipidDallas, alex_tucson and 47 others
Reply Quote Save Share Report

Similar Threads

Survodutide MASH Phase 2b — histological improvement data9 replies
Semaglutide and MASH — liver fat reduction quantification13 replies
Non-invasive MASH biomarkers — FibroScan, ELF, FIB-4 on GLP-110 replies
ALT normalization rates on GLP-1 — pooled trial data20 replies
GLP-1 hepatoprotection — direct vs indirect mechanisms16 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register