DanielChem_CHI said:Albumin binding above 99% is the whole reason weekly dosing works, and it is also why the trough matters more than the peak.
Second this. I had assumed I was the exception until I read this.
DanielChem_CHI said:Albumin binding above 99% is the whole reason weekly dosing works, and it is also why the trough matters more than the peak.
Adding the part of the answer the thread has not reached. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.
One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.
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Browse GL BiochemOne thing that is still open after DanielChem_CHI’s answer:
What would you measure differently if you were starting again?
dave_SLC said:One practical note: write down what you did and when, before you need it.
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.
Ask again with the specifics and you will get a better answer than this one.