Resistance training prevents 73% lean mass loss on semaglutide — RCT review

MikeFit_NJ said:

There is also a quality change that the scan cannot see.

OMG yes. lean mass + resistance training is the combo. Can confirm.

One thing that is still open after Dr.SurgeonPGH’s answer:

Whether resistance training and protein change the ratio or only the absolute amount?

DataDave said:

lean mass + resistance training is the combo.

Coming at DataDave’s question from a different direction. Training does two things here and only one of them is on the scale. It protects lean mass — which is the reason to do it — and it contributes modestly to the deficit, which is the reason people start and then quit when the arithmetic disappoints them. In a deep deficit, resistance work is the priority and high-volume cardio competes with recovery.

Happy to go further on any of that.

Closing the loop on my own question.

Second scan under matched conditions, six months apart, same time of day: the lean number came back nearly a kilo higher than the panic scan. Strength was up throughout.

Dr.ObesityLA said:

Training does two things here and only one of them is on the scale.

Right, and protein targets should be set on a reference weight rather than current weight. Setting 1.6 g/kg on a starting weight of 130kg produces a target nobody hits on a suppressed appetite.

Correct me if the detail matters more than I have assumed.