Retatrutide resting energy expenditure — need advice

roxy_nash said:

Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

SarahChen_PharmD said:

The phase 2 numbers were about 24% mean weight loss at 48 weeks on the top dose, with the curve still descending at the end of the study.

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

roxy_nash said:

Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

I would rather be corrected than agreed with, if it comes to it.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Carry on.