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ForumsLab Results & BiomarkersCholesterol dropped 80 points and my doc is shook Page 2

Cholesterol dropped 80 points and my doc is shook

dan_philly Sat, May 9, 2026 at 10:28 AM 23 replies 941 viewsPage 2 of 5
HPLC_Greg
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May 10, 2026 at 9:43 AM#6
Dr.NutriCornell said:
Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data: Category Marker Before After…

Careful with treating an unchanged LDL-C as a failure. If ApoB and triglycerides both fell, the particle picture improved regardless of what the calculated LDL says.

Last edited: May 10, 2026 at 3:43 PM
36 14SallyK_inj, CryptoCarl, MariaRD and 33 others
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hank_denver
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Sep 2024
Denver, CO
May 10, 2026 at 6:57 PM#7
dan_philly said:
Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.

Advanced lipoprotein testing on the lipid panel — going beyond standard lipid panel:

MarkerBaselineMonth 8Clinical Meaning
LDL-P1569969Particle count (more precise than LDL-C)
Small dense LDL69%29%Atherogenic pattern
Remnant cholesterol3718Triglyceride-rich lipoproteins
oxLDL7447Oxidative stress marker

The shift from small dense to large buoyant LDL is particularly important — it represents a fundamental change in the atherogenic profile.

37 15raj_cambridge, ingrid_STO, pete_nash and 34 others
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pat_auckland
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Jun 2024
Auckland, NZ
May 11, 2026 at 4:11 AM#8
HPLC_Greg said:
Careful with treating an unchanged LDL-C as a failure.

Comprehensive lipid panel update relevant to the lipid panel:

MarkerBaseline6 Months12 MonthsReference
Total Cholesterol255220180<200
LDL170115100<100
HDL434662>40
Triglycerides275170120<150
LDL-P14751125875<1000

The triglyceride drop is the most impressive. My cardiologist reduced my statin dose based on these results.

Last edited: May 11, 2026 at 8:11 AM
38 16LarryQC_SD, wanda_boise, NurseAsh_DET and 35 others
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anna.melb_AU
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Apr 2024
Melbourne, AU
May 11, 2026 at 1:25 PM#9

A narrower follow-up, since the general answer is now clear:

How long did you give it before you decided it was working?

Last edited: May 11, 2026 at 5:25 PM
39 17tammy_FL, Dr.LipidDallas, alex_tucson and 36 others
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dan_philly
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Philadelphia, PA
May 13, 2026 at 9:43 AM#10

Closing the loop on my own question.

Update: the thing I was blaming turned out not to be the cause. Leaving the original post as written rather than editing it, so the mistake stays visible for whoever searches this next.

Last edited: May 13, 2026 at 12:43 PM
3 3EndoResFellow, PharmacoVig_BOS, SurmountFan_IN
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