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ForumsCardiovascular OutcomesHas anyone dealt with tirzepatide cardiovascular safety? Page 7

Has anyone dealt with tirzepatide cardiovascular safety?

carlos_SATX Thu, Sep 18, 2025 at 10:20 PM 41 replies 1,657 viewsPage 7 of 9
ricardo_MIA
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Sep 29, 2025 at 7:31 PM#31
Dr.PeteFamMed said:
Say what you would expect to see if you were wrong, before you look.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

Last edited: Sep 30, 2025 at 12:31 AM
22 22JakeSmashed95, NauseaFreeNow, SteveThurs and 19 others
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DanielChem_CHI
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Sep 30, 2025 at 2:42 PM#32
Dr.PeteFamMed said:
Say what you would expect to see if you were wrong, before you look.

This answered a question I did not know how to ask.

Last edited: Sep 30, 2025 at 4:42 PM
21 21Dr.DermMIA, fiona_VT, denise_HTX and 18 others
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Dr.EM_Chicago
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Oct 1, 2025 at 9:54 AM#33

Clinical perspective, offered as context rather than as advice. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

20 20Dr.ReproEndo, lucas_SP_BR, lisa_labSD and 17 others
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MariaRD
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Oct 2, 2025 at 5:06 AM#34
Dr.EM_Chicago said:
Start from the measurement rather than the conclusion.

Mine went the same way, slower. The detail I would add is minor and it is already implied above.

19 19rick_sfbay, maria_elpaso, anders_CPH and 16 others
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pat_auckland
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Oct 3, 2025 at 12:19 AM#35
Dr.EM_Chicago said:
Start from the measurement rather than the conclusion.

Adding the part of the answer the thread has not reached. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Worth separating that from cardiovascular outcomes, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

18 18dan_philly, MeganSA_TX, LarryQC_SD and 15 others
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