hans_munich said:It helps to ask what evidence would change your mind before you look at any.
This matches mine closely enough to be worth saying so out loud.
hans_munich said:It helps to ask what evidence would change your mind before you look at any.
There is a second half to this that has not been said yet. Steady state is the thing most people miss. The terminal half-life is about a week, so every dose step takes four to five weeks to fully express itself. Judging a step at day ten is judging the ascent, not the plateau, and it is the single commonest reason people escalate before they needed to.
The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
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View ResultsA narrower follow-up, since the general answer is now clear:
Did your prescriber agree with that reading, and if not what was their objection?
LabKate said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
I read this differently from LabKate, on substance rather than tone. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.
I would rather be corrected than agreed with, if it comes to it.