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ForumsPublic SquareSemaglutide and gallbladder disease risk — my results so far Page 6

Semaglutide and gallbladder disease risk — my results so far

lisa_labSD Wed, Jun 4, 2025 at 10:48 PM 44 replies 2,339 viewsPage 6 of 9
kevin_tulsa
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Sep 9, 2025 at 6:56 AM#26
labquiet_amy said:
For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and…

Saving this. It is the first explanation that did not require me to already understand it. Sending this to two other people who asked me the same thing last week.

40 13fiona_glasgow, Dr.RheumBOS, greg_boulder and 37 others
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james_edin
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Sep 22, 2025 at 5:59 AM#27

From the other side of the consultation, briefly. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

41 14Dr.PathRoch, mona_PHX, andrew_nyc and 38 others
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Dr.NephBHM_UK
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Oct 5, 2025 at 4:54 AM#28
james_edin said:
Worth answering the question that was asked rather than the one behind it.

Adding a me-too, because a thread of one person's experience is not much use.

42 15PharmacoVig_BOS, SurmountFan_IN, PeptideChemSF and 39 others
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dan_philly
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Oct 18, 2025 at 3:41 AM#29
james_edin said:
Worth answering the question that was asked rather than the one behind it.

There is a second half to this that has not been said yet. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Last edited: Oct 18, 2025 at 6:41 AM
43 16Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 40 others
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lisa_labSD
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San Diego, CA
Oct 31, 2025 at 2:22 AM#30

Reporting back.

Following this thread I went back and re-read the extension data properly. The point about trough rather than peak explains the pattern I was seeing on day six, which I had been blaming on the vial.

15 13cory_ATX, lori_vegas, Dr.PulmRoch and 12 others
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