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ForumsPsychological & BehavioralThe food noise is gone and honestly it is kind of unsettling — what worked for you? Page 3

The food noise is gone and honestly it is kind of unsettling — what worked for you?

jennifer_SEA Wed, Mar 26, 2025 at 7:09 PM 14 replies 1,554 viewsPage 3 of 3
Dr.ReproEndo
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Mar 31, 2025 at 7:44 PM#11
BariatricNurseD said:
Phantom hunger vs real hunger on food noise: learning to distinguish between the two has been a revelation.

Neuroscience perspective on food noise:

GLP-1 receptors are expressed throughout the CNS, with high density in the hypothalamic arcuate nucleus, area postrema, and — critically — the mesolimbic reward pathway[1].

This is directly relevant to food noise because the central effects of GLP-1 agonists extend far beyond simple appetite suppression. The reduction in "food noise" that patients describe is likely mediated by modulation of dopaminergic signaling in the VTA and nucleus accumbens.

The emerging data on reduced addictive behaviors (alcohol, gambling) further supports this mechanism. food noise should be understood in this broader neurobiological context.

References:
[1] Merchenthaler I, et al. J Comp Neurol. 1999;403(2):261-280.
26 1mona_PHX, andrew_nyc, Dr.EndoEP and 23 others
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AmyNC_wife
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Apr 1, 2025 at 10:54 AM#12
TinaHashiRN said:
KevinCompounds said: ...regarding food noise mechanism of action...

That reframing is the part I needed.

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claudia_zurich
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Apr 2, 2025 at 2:04 AM#13
BariatricNurseD said:
Phantom hunger vs real hunger on food noise: learning to distinguish between the two has been a revelation.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

24 24Dr.LipidDallas, alex_tucson, kevin_tulsa and 21 others
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Dr.RaviCardio
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Apr 2, 2025 at 5:14 PM#14

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

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Admin
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Apr 3, 2025 at 8:24 AM#15

Moderator note: a couple of off-topic posts removed.

22 22PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 19 others
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