Muscle protein synthesis rates on GLP-1 — 6 month update

SleepDoc_PDX said:

DEXA scan update relevant to protein intake: Scanned at months 0, 6, and 12.

Right, and protein targets should be set on a reference weight rather than current weight. Setting 1.6 g/kg on a starting weight of 130kg produces a target nobody hits on a suppressed appetite.

Worth separating that from lean-mass preservation, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

That is the short version; the long version is somebody else's post.

PeptideSynthNJ said:

The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Thank you for spelling out the reasoning rather than just the conclusion.

Clinical perspective, offered as context rather than as advice. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

hans_munich said:

It is worth asking what the claim would look like if it were false.

Adding a me-too, because a thread of one person's experience is not much use. I had assumed I was the exception until I read this.

Moderator note: a couple of off-topic posts removed. Report rather than reply if it drifts again.