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ForumsPublic SquareNovo Nordisk CagriSema Phase 3 results — need advice Page 9

Novo Nordisk CagriSema Phase 3 results — need advice

mike_mod Tue, Nov 18, 2025 at 8:31 PM 43 replies 1,982 viewsPage 9 of 9
MASHdoc_SA
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Dec 10, 2025 at 4:06 AM#41
lisa_labSD said:
Say what you would expect to see if you were wrong, before you look.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Taking it to my next appointment.

12 12TirzTom, TrialTracker_MD, JennaRN and 9 others
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TrialNerd_Beth
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Dec 11, 2025 at 2:19 AM#42

From the other side of the consultation, briefly. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

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Admin
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Dec 12, 2025 at 12:32 AM#43

Moderator note: a couple of off-topic posts removed. Thread quality here is what the rules are for. Keep it up.

Last edited: Dec 12, 2025 at 4:32 AM
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PeptideChemSF
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Dec 12, 2025 at 10:46 PM#44
TrialNerd_Beth said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

There is a second half to this that has not been said yet. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Worth separating that from the trial evidence, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

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raj_cambridge
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Dec 13, 2025 at 9:01 PM#45

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

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