South Korea Ozempic availability — 12 month update

Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

rachel_ABQ said:

There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

Correct me if the detail matters more than I have assumed.

rachel_ABQ said:

There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

rachel_ABQ has the substance of this right. The condition it depends on is worth stating. Albumin binding above 99% is the whole reason weekly dosing works, and it is also why the trough matters more than the peak. People who dose late are not losing a peak, they are letting the trough fall, and the appetite effect tracks the trough.

Correct me if the detail matters more than I have assumed.

rachel_ABQ said:

There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

This is exactly what I could not find anywhere else. Taking it to my next appointment.

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Report rather than reply if it drifts again.