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ForumsOral GLP-1 AgonistsPLEASE just give me a pill already I hate needles so much — looking for input Page 2

PLEASE just give me a pill already I hate needles so much — looking for input

RegAffairsDC Mon, Jun 23, 2025 at 6:04 PM 12 replies 1,406 viewsPage 2 of 3
SleepDoc_PDX
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Jun 24, 2025 at 5:00 AM#6

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

9 4pete_nash, hank_denver, carlos_SATX and 6 others
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marco_milano
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Jun 24, 2025 at 9:19 AM#7

A narrower follow-up, since the general answer is now clear:

Whether the fasting requirement is as strict in practice as the label implies, and what people actually see when they get it wrong?

8 3alex_tucson, kevin_tulsa, Dr.PainCLE and 5 others
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Dr.GutHealth
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Jun 24, 2025 at 1:38 PM#8
SleepDoc_PDX said:
Say what you would expect to see if you were wrong, before you look.

Coming at SleepDoc_PDX’s question from a different direction. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

7 2jennifer_SEA, tyler_CSCS, VanRx_Mike and 4 others
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RegAffairsDC
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Jun 24, 2025 at 5:57 PM#9

Reporting back.

Update — I went back to the injectable. Not because the tablet did not work, but because the fasting window and my mornings were never going to agree.

6 1sean_dublin, hannah_MT, Dr.SportsMedIN and 3 others
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DataDave
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Jun 25, 2025 at 2:40 PM#10
Dr.GutHealth said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

Dr.GutHealth has the substance of this right. The condition it depends on is worth stating. The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest. Where it bites is in the first fortnight, when people conclude the tablet does nothing.

42 15Dr.GutHealth, amsterdam_pete, LondonLisa and 39 others
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