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Admin Mon, Feb 19, 2024 at 5:20 PM 185 replies 24,631 viewsPage 12 of 20
KevinCompounds
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Feb 18, 2025 at 10:09 PM#56
TrialTracker_MD said:
Practical: whatever you change, write down the date and the reason.

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

46 19jennifer_SEA, tyler_CSCS, VanRx_Mike and 43 others
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kim_atl_prep
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Feb 28, 2025 at 10:53 AM#57
TrialTracker_MD said:
Practical: whatever you change, write down the date and the reason.

This is exactly what I could not find anywhere else. Adding it to my notes with a link back to this thread.

47 20BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 44 others
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SleepDoc_PDX
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Mar 9, 2025 at 11:31 PM#58

Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

48 21carlos_SATX, sophie_paris, mel_PDX and 45 others
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SarahChen_PharmD
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Mar 19, 2025 at 12:03 PM#59
SleepDoc_PDX said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Can confirm. Same sequence, different timescale. I had assumed I was the exception until I read this.

49 22TinaHashiRN, robert_kc, dan_philly and 46 others
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NicoleRaleigh
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Raleigh, NC
Mar 29, 2025 at 12:30 AM#60
SleepDoc_PDX said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Coming at SleepDoc_PDX’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

21 19mike_nyc, VendorMark, COA_Karl and 18 others
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