TrialTracker_MD said:For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.
Saving this. It is the first explanation that did not require me to already understand it. I will report back once I have actually tried it.
Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
sean_dublin said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
This is my experience too, for whatever a second data point is worth.
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View Resultssean_dublin said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Adding the part of the answer the thread has not reached. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.
Closing the loop on my own question.
Update — tachyphylaxis to the gastric effect, persistence of the appetite effect. Two curves, and I had been watching the wrong one.