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ForumsOral GLP-1 AgonistsOrforglipron liver safety profile — hepatic considerations Page 3

Orforglipron liver safety profile — hepatic considerations

MASHdoc_SA Thu, May 28, 2026 at 5:37 PM 16 replies 520 viewsPage 3 of 4
stefan_berlin
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May 30, 2026 at 6:21 PM#11
Dr.KarenChen said:
The manufacturing argument is the underrated one.

Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.

33 6NeuroNate, JessicaH_TX, KevinCompounds and 30 others
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roxy_nash
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May 31, 2026 at 10:00 AM#12

From the other side of the consultation, briefly. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

34 7roxy_nash, tony_orlando, Dr.NephBHM_UK and 31 others
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BethLabQueen
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Jun 1, 2026 at 1:39 AM#13
PharmHunterJen said:
The liver data is among the strongest non-weight findings in the class.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

Last edited: Jun 1, 2026 at 2:39 AM
35 8lori_vegas, Dr.PulmRoch, maya_sedona and 32 others
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Dr.AddMedPHL
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Jun 1, 2026 at 5:19 PM#14

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

Ask again with the specifics and you will get a better answer than this one.

36 9TomFromTexas, mike.trainer_LA, sarah_nash92 and 33 others
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Admin
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Jun 2, 2026 at 8:59 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Carry on.

37 10PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 34 others
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