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ForumsDosing & ProtocolsInjection technique: subcutaneous depot formation and absorption — 12 month update Page 5

Injection technique: subcutaneous depot formation and absorption — 12 month update

Dr.RenalNash Thu, Feb 8, 2024 at 9:06 AM 46 replies 2,824 viewsPage 5 of 10
PharmD_Rodriguez
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Feb 11, 2024 at 12:51 AM#21

Clinical perspective, offered as context rather than as advice. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

35 8paul_denver, TinaHashiRN, robert_kc and 32 others
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sarah.morrison
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Feb 11, 2024 at 2:56 PM#22
PharmD_Rodriguez said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Can confirm. Same sequence, different timescale. Nothing to add that would improve it.

Last edited: Feb 11, 2024 at 3:56 PM
36 9roxy_nash, tony_orlando, Dr.NephBHM_UK and 33 others
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HealthEcon_DC
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Feb 12, 2024 at 5:00 AM#23
PharmD_Rodriguez said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Coming at PharmD_Rodriguez’s question from a different direction. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

37 10KevinCompounds, TirzTom, TrialTracker_MD and 34 others
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VendorMark
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Feb 12, 2024 at 7:04 PM#24

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Last edited: Feb 12, 2024 at 9:04 PM
38 11Dr.PeteFamMed, claudia_zurich, nancy_portland and 35 others
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PharmacoVig_BOS
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Feb 13, 2024 at 9:08 AM#25

One thing that is still open after PharmD_Rodriguez’s answer:

How would you tell the difference between that and the alternative explanation?

39 12LabKate, kate.chem, DataDave and 36 others
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