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ForumsMarketplace & ListingsCompounded tirzepatide availability tracker — my results so far Page 2

Compounded tirzepatide availability tracker — my results so far

KevinCompounds Fri, Apr 5, 2024 at 12:18 PM 34 replies 2,155 viewsPage 2 of 7
Dr.PeteFamMed
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Apr 5, 2024 at 2:47 PM#6
Dr.RaviCardio said:
Steady state is faster than people expect: half-life about five days, so you are at plateau in roughly three to four weeks rather than five.

I read this differently from Dr.RaviCardio, on substance rather than tone. The "tirzepatide is simply better" summary irritates me. It is better on mean weight loss, and the cardiovascular outcome evidence is far thinner than semaglutide's. If the reason for treating is cardiovascular risk rather than weight, the evidence base points the other way.

36 6hyun_seoul, jim_asheville, matt_MKE and 33 others
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Dr.NateNeph
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Apr 5, 2024 at 3:45 PM#7

The figures, for anyone assembling their own picture. Two things anyone can check: a state licence number for a 503A, and an FDA outsourcing-facility registration for a 503B. Both are publicly searchable, and a pharmacy unwilling to give you either has answered the question.

35 5NauseaFreeNow, SteveThurs, B12Beth and 32 others
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anders_CPH
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Apr 5, 2024 at 4:43 PM#8
Dr.PeteFamMed said:
The "tirzepatide is simply better" summary irritates me.

There is a second half to this that has not been said yet. Resolution therefore closed the doors unevenly, and the asymmetry follows from the bulks lists. For 503B the shortage clause was the only route to these molecules, so that route shut completely. A 503A pharmacy can still argue a doorway via "component of an approved drug" — but only for the substance in the form present in the approved product, which is exactly where the base-versus-salt argument lives, and it does nothing about the copy restriction, which came back into force on resolution.

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nick_SD_fit
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Apr 5, 2024 at 5:41 PM#9

A narrower follow-up, since the general answer is now clear:

Whether anyone has held 10mg long term rather than climbing, and what happened over the following year?

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KevinCompounds
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Apr 5, 2024 at 10:19 PM#10

Closing the loop on my own question.

Reporting back after another eight months at the same dose. Still losing slowly, no new side effects, and no reason I can find to climb further.

31 4NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 28 others
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