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ForumsPharmacology & MechanismsIncretin effect in healthy vs T2DM — 12 month update Page 4

Incretin effect in healthy vs T2DM — 12 month update

marco_milano Mon, Oct 20, 2025 at 2:49 AM 28 replies 1,548 viewsPage 4 of 6
JenPlateau
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Oct 24, 2025 at 8:43 PM#16

Adding the clinical framing, because it changes how the question reads. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

Last edited: Oct 25, 2025 at 2:43 AM
27 0HPLC_Greg, LibrarianMeg, bri_stats and 24 others
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lisa_labSD
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Oct 25, 2025 at 1:05 PM#17

Adding the clinical framing, because it changes how the question reads. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

28 1maya_sedona, stefan_berlin, Dr.EM_Chicago and 25 others
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mike_mod
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Oct 26, 2025 at 5:26 AM#18
lisa_labSD said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Same experience, arrived at from the opposite direction.

Last edited: Oct 26, 2025 at 7:26 AM
29 2DoseLogDan, SleepFixSam, PurityPaulOR and 26 others
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tony_orlando
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Oct 26, 2025 at 9:47 PM#19
lisa_labSD said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Coming at lisa_labSD’s question from a different direction. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

30 3CanadaChris, ZaraB_AL, JakeSmashed95 and 27 others
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PedsEndoPhilly
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Oct 27, 2025 at 2:08 PM#20

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.

Last edited: Oct 27, 2025 at 7:08 PM
2 0MikeNYC_runner
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