Reconstitution calculator — 12 month update

Clinical perspective, offered as context rather than as advice.

Reconstitution tip for anyone mixing dosing arithmetic from lyophilized powder: use bacteriostatic water, NOT sterile water. The benzyl alcohol in BAC water preserves multi-dose vials for up to 28 days.

Inject the water slowly down the side of the vial. NEVER shake — gentle swirling only until fully dissolved. Should be crystal clear with no particles.

One thing that is still open after adam_van’s answer:

How long did you give it before you decided it was working?

Dr.ReproEndo said:

Reconstitution tip for anyone mixing dosing arithmetic from lyophilized powder: use bacteriostatic water, NOT sterile water.

Quick syringe math for dosing arithmetic dosing: if your vial is reconstituted at 5mg/2mL, that's 2.5mg/mL. For a 0.25mg dose you need 0.1mL = 10 units on an insulin syringe.

I keep a chart on my fridge:

• 0.25mg = 10 units
• 0.5mg = 20 units
• 1.0mg = 40 units
• 1.25mg = 50 units

Always double-check your concentration before drawing up!

Dr.ReproEndo said:

Reconstitution tip for anyone mixing dosing arithmetic from lyophilized powder: use bacteriostatic water, NOT sterile water.

Ongoing cost tracking for dosing arithmetic — transparency for the community:

Monthly medication cost: $125
Supplies (syringes, BAC water, alcohol swabs): ~$8/month
Janoshik testing: ~$10/month (amortized quarterly)
Lab work: ~$55/month (amortized quarterly)
Total: ~$205/month

Compare to brand Wegovy at $1315/month without insurance. Compounded is roughly 90% cheaper for what I have found to be clinically equivalent medication.

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Carry on.