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ForumsDosing & ProtocolsHalf-life implications for missed doses — anyone have experience? Page 3

Half-life implications for missed doses — anyone have experience?

matt_MKE Wed, Apr 1, 2026 at 11:48 PM 26 replies 836 viewsPage 3 of 6
Dr.RenalNash
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Apr 2, 2026 at 10:38 AM#11
hans_munich said:
Worth answering the question that was asked rather than the one behind it.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

31 4wei_SG, cory_ATX, lori_vegas and 28 others
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HealthEcon_DC
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Apr 2, 2026 at 5:06 PM#12
BethLabQueen said:
Agreed, and the adaptation point cuts both ways: tachyphylaxis to gastric emptying is why tolerability improves, and it is also why people who were…

That reframing is the part I needed.

Last edited: Apr 2, 2026 at 7:06 PM
32 5JessicaH_TX, KevinCompounds, TirzTom and 29 others
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Dr.NutriCornell
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Apr 2, 2026 at 11:34 PM#13
hans_munich said:
Worth answering the question that was asked rather than the one behind it.

Pushing back on hans_munich here. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

Last edited: Apr 3, 2026 at 1:34 AM
33 6laura_annarbor, JenMemphis, pat_auckland and 30 others
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kate.chem
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Apr 3, 2026 at 6:03 AM#14

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

34 7jennifer_SEA, tyler_CSCS, VanRx_Mike and 31 others
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Admin
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Apr 3, 2026 at 12:32 PM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Report rather than reply if it drifts again.

35 8PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 32 others
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