From the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Dr.KarenChen said:The mechanism and the magnitude are separate questions.
This is my experience too, for whatever a second data point is worth. Posting only so the count is not one.
Dr.KarenChen said:The mechanism and the magnitude are separate questions.
Adding the part of the answer the thread has not reached. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsAdding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.
Following on from Dr.KarenChen — and this may be the naive question:
Was that from a primary source or from a summary of one?