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ForumsDosing & ProtocolsSemaglutide titration: 0.25→0.5→1.0→1.7→2.4mg optimal schedule Page 11

Semaglutide titration: 0.25→0.5→1.0→1.7→2.4mg optimal schedule

Dr.Martinez Mon, Feb 26, 2024 at 4:00 PM 332 replies 13,278 viewsPage 11 of 20
julia.endo
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Mar 16, 2024 at 2:00 AM#51
dan_philly said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

46 21anna.melb_AU, mark_tokyo, hans_munich and 43 others
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Dr.MetabolicMD
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Mar 16, 2024 at 2:21 PM#52
dan_philly said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

45 20PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 42 others
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JenPlateau
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Mar 17, 2024 at 2:42 AM#53

From the other side of the consultation, briefly. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

Last edited: Mar 17, 2024 at 8:42 AM
44 19RunnerRach, TrialNerd_Beth, HPLC_Greg and 41 others
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AussieAnna
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Mar 17, 2024 at 3:03 PM#54
JenPlateau said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Same pattern here, and in the same order. Nothing to add that would improve it.

43 18bri_stats, pete_manc_UK, anna.melb_AU and 40 others
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Dr.KarenChen
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Mar 18, 2024 at 3:23 AM#55
JenPlateau said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

There is a second half to this that has not been said yet. Holding longer is the underrated move. A step that is uncomfortable at week two is frequently comfortable at week six with no change in dose, because the gastric-emptying component tachyphylaxes while the appetite effect persists. Escalating at week two throws that adaptation away.

42 17sarah_nash92, FitDadDave, RunnerRach and 39 others
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