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ForumsNutrition & SupplementationBone broth and collagen — anyone have experience?

Bone broth and collagen — anyone have experience?

oliver_london Mon, Jun 23, 2025 at 7:30 AM 12 replies 1,574 viewsPage 1 of 3
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oliver_london
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Jun 23, 2025 at 7:30 AM#1

A reference post rather than a discussion. Corrections are the point; I would rather this be right than mine. It is about protein intake, and it is deliberately narrow — everything I am not confident about is marked as such.

What is actually established

Distribution matters less than total but it is not nothing. Roughly 25 to 40g per sitting with enough leucine to trigger synthesis, three or four times a day, is more effective than the same total in one enormous evening meal — and on a suppressed appetite the enormous evening meal is the one you will not finish anyway.

The condition it depends on

The caveat that reference weight and current weight are different numbers. Using current weight at the start of a large loss produces a target that is both unachievable and unnecessary.

The practical version

The arithmetic that makes it tractable: reference weight in kg times 1.6 gives the target; divide by four for a per-sitting figure; then find four foods that hit that figure in a volume you can actually finish. Most people need two of the four to be liquid or semi-liquid early on.

What I am not sure about

The bit I cannot resolve on my own is whether the RDA is the wrong reference entirely during rapid weight loss, and what the actual target should be. Practical detail welcome, however dull — the duller the better.

— oliver_london · corrections welcome and will be edited into this post with credit
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Dr.PeteFamMed
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Jun 23, 2025 at 7:36 AM#2
oliver_london said:
Distribution matters less than total but it is not nothing.

Agreeing with oliver_london, and the qualification matters more than the agreement. On a suppressed appetite the winning strategy is protein density per unit of volume, not per calorie. Isolate powders, Greek yoghurt and cottage cheese, egg whites, lean fish, and tinned tuna all deliver a lot of protein in a small physical volume. Front-load it: appetite is usually least suppressed in the first hours after waking and worst on the day or two after dosing, so get the majority in early in the day and early in the week.

Last edited: Jun 23, 2025 at 8:36 AM
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julia.endo
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Jun 23, 2025 at 7:42 AM#3
oliver_london said:
Distribution matters less than total but it is not nothing.

I will push back on the powder-first advice. It works and it also trains people out of eating food, and when the drug stops the habits are what remain. Getting protein from meals is slower and holds up better afterwards.

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Dr.RheumBOS
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Jun 23, 2025 at 7:48 AM#4

Taking the question as asked, rather than the general version of it. The RDA is the wrong reference and it is worth understanding why. 0.8 g/kg is the intake at which nitrogen balance is not negative in healthy weight-stable adults — a floor for deficiency prevention, not an optimum, and derived in a population that is not in a deficit. In a substantial energy deficit, protein requirement rises because amino acids are being oxidised for energy and because muscle protein synthesis is blunted. The literature on preserving lean mass during weight loss lands around 1.4 to 2.0 g/kg of reference body weight, which is roughly two to two and a half times the RDA.

I would rather be corrected than agreed with, if it comes to it.

Last edited: Jun 23, 2025 at 1:48 PM
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BrianDallas92
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Jun 23, 2025 at 8:19 AM#5
Dr.PeteFamMed said:
On a suppressed appetite the winning strategy is protein density per unit of volume, not per calorie.

Mine went the same way, slower. The detail I would add is minor and it is already implied above.

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