SleepDoc_PDX said:Practical: whatever you change, write down the date and the reason.
Thank you for spelling out the reasoning rather than just the conclusion.
Clinical perspective, offered as context rather than as advice. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.
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Browse GL Biochemandrew_nyc said:It helps to ask what evidence would change your mind before you look at any.
There is a second half to this that has not been said yet. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.
The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.