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ForumsNutrition & SupplementationVitamin D optimization on GLP-1 — need advice

Vitamin D optimization on GLP-1 — need advice

KetoKyle Tue, Dec 9, 2025 at 12:44 AM 10 replies 1,000 viewsPage 1 of 2
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KetoKyle
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Dec 9, 2025 at 12:44 AM#1

Six months of eating roughly 1,100 calories a day and my ferritin has halved, which I did not connect to the intake until somebody pointed it out.

What I am after is which deficiencies actually show up when intake drops this far, and which are worth testing rather than supplementing blind.

Practical detail welcome, however dull — the duller the better.

42 12laura_annarbor, JenMemphis, pat_auckland and 39 others
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PurityPaulOR
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Dec 9, 2025 at 12:55 AM#2
KetoKyle said:
Six months of eating roughly 1,100 calories a day and my ferritin has halved, which I did not connect to the intake until somebody pointed it out.

Vitamin and mineral labs to check while on micronutrients — my doctor orders these quarterly:

  • B12: Can drop due to reduced GI absorption. Mine went from 650 to 380 — now supplementing.
  • Iron/Ferritin: Reduced food intake = reduced iron. Ferritin dropped from 65 to 22. Supplementing.
  • Vitamin D: Was already low (20 ng/mL), now taking 5000 IU daily.
  • Folate: Stable, no issues.
  • Zinc: Slightly low, added a multivitamin with zinc.

Nutritional deficiencies are a real risk when you're eating significantly less. Don't skip your labs!

41 11MikeNYC_runner and 38 others
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patPC_UT
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Park City, UT
Dec 9, 2025 at 1:06 AM#3
PurityPaulOR said:
Vitamin and mineral labs to check while on micronutrients — my doctor orders these quarterly: B12: Can drop due to reduced GI absorption.

Vitamin D levels and micronutrients: an often-overlooked connection. Obese individuals store vitamin D in adipose tissue, making it less bioavailable. As you lose fat, vitamin D can actually increase WITHOUT supplementation.

My trajectory: Baseline 18 ng/mL → Month 6 (with supplement) 42 ng/mL → Month 12 48 ng/mL. Target is 40-60 ng/mL. Adequate vitamin D supports immune function, bone health, and mood — all relevant during weight loss.

40 10TomFromTexas, mike.trainer_LA, sarah_nash92 and 37 others
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bbq_ray_KC
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Dec 9, 2025 at 1:17 AM#4
KetoKyle said:
Six months of eating roughly 1,100 calories a day and my ferritin has halved, which I did not connect to the intake until somebody pointed it out.

Same pattern here, and in the same order.

39 9WendyG_ATL, SaraMom3, Dr.MetabolicMD and 36 others
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Dr.PathRoch
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Rochester, MN
Dec 9, 2025 at 2:16 AM#5

Adding the clinical framing, because it changes how the question reads.

Iron studies on micronutrients — important especially for women:

MarkerBaselineMonth 6After Supplementation
Ferritin582158
Iron886381
TIBC323393333
Transferrin Sat31%18%26%

My ferritin cratered at month 6 from reduced dietary intake. Iron bisglycinate 36mg with vitamin C brought it back up. Don't wait for anemia symptoms — test proactively.

38 8Dr.MetabolicMD, RetaRick_CA, JenPlateau and 35 others
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