Clinical perspective, offered as context rather than as advice. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.
The figures, for anyone assembling their own picture. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.
A narrower follow-up, since the general answer is now clear:
What would you measure differently if you were starting again?
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Browse GL BiochemDr.RaviCardio said:Practical: whatever you change, write down the date and the reason.
I read this differently from Dr.RaviCardio, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.