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ForumsNutrition & SupplementationProbiotics on GLP-1 — strain-specific evidence review Page 2

Probiotics on GLP-1 — strain-specific evidence review

Dr.GutHealth Thu, Apr 30, 2026 at 7:37 PM 28 replies 892 viewsPage 2 of 6
DoseLogDan
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Apr 30, 2026 at 8:53 PM#6
Dr.GutHealth said:
The RDA is the wrong reference and it is worth understanding why.

DEXA scan update relevant to protein intake:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

BaselineMonth 6Month 12
Total mass257 lbs232 lbs194 lbs
Fat mass97 lbs77 lbs44 lbs
Lean mass150 lbs152 lbs151 lbs
Body fat %42%32%23%

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.6g/kg protein. The protein intake discussion needs to include body comp data, not just scale weight.

23 18newstart_MO, mia_MS2, LeilaHI and 20 others
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dan_philly
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Apr 30, 2026 at 9:23 PM#7

One thing that is still open after JenPlateau’s answer:

How people are hitting a protein target on a genuinely suppressed appetite, because volume is the binding constraint rather than willingness?

Last edited: May 1, 2026 at 12:23 AM
22 17AmyNC_wife, SkepticalSean, Dr.CardioMD and 19 others
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DeniseRN_TPA
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Apr 30, 2026 at 9:52 PM#8
DoseLogDan said:
DEXA scan update relevant to protein intake: Scanned at months 0, 6, and 12.

Coming at DoseLogDan’s question from a different direction. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

21 16tommy_boulder, hyun_seoul, jim_asheville and 18 others
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Dr.GutHealth
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Apr 30, 2026 at 10:22 PM#9

OP back with an update, since a thread like this is useless without one.

Reporting back — setting the target on reference weight rather than current weight turned an impossible number into a boring one.

20 15Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 17 others
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cory_ATX
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May 1, 2026 at 12:44 AM#10
DeniseRN_TPA said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Agreed on the target, with the caveat that reference weight and current weight are different numbers. Using current weight at the start of a large loss produces a target that is both unachievable and unnecessary.

2 0tane_welly, Dr.PathRoch
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