How to commission independent testing — need advice

julia.endo said:

Third-party testing services for certificates of analysis besides Janoshik: Janoshik: Gold standard for peptide community, ~$156, 10-14 day turnaround…

COA red flags for certificates of analysis — here's what to look for when reviewing a Certificate of Analysis:

• No HPLC data: If there's no chromatography graph, it's not a real COA
• Exact 100% purity: Suspicious — real testing always shows slight variation
• No batch number: Can't trace back to specific production
• No endotoxin testing: For injectables, this is essential
• Template looks like it was made in Word: Professional labs have standardized formats

I have seen fake COAs that are literally photoshopped. Always verify independently if possible.

BethLabQueen said:

Agreed, and mass spec answers a question purity does not: identity.

This is exactly what I could not find anywhere else.

julia.endo said:

Third-party testing services for certificates of analysis besides Janoshik: Janoshik: Gold standard for peptide community, ~$156, 10-14 day turnaround…

Mass spectrometry confirmation for certificates of analysis: beyond HPLC purity, mass spec tells you the molecule's exact molecular weight. This confirms identity — not just purity.

Why this matters: HPLC can show you a "pure" compound, but if it's pure of the WRONG compound, purity is meaningless. Mass spec at m/z 4113.58 Da confirms it's actually semaglutide. My Janoshik report includes both HPLC and mass spec.

If your testing provider only offers HPLC, consider upgrading to include mass spec for at least your first batch from a new vendor.

wendy_avl said:

Two reports on the same product from two laboratories, four percentage points apart, and no method stated on either.

My vendor review relevant to certificates of analysis: ordered 3 times from my current compounder. Consistency has been excellent.

Shipping: Next-day with cold pack
Packaging: Professional, discreet, proper labeling with lot/batch numbers
Purity: 98.0% average across orders (Janoshik verified)
Customer service: Responsive within 2 hours
Price: $152/month for tirzepatide 10mg equivalent

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Thread quality here is what the rules are for. Keep it up.