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ForumsCOA & Analytical TestingRed flags on COAs — my results so far Page 2

Red flags on COAs — my results so far

pam_columbus Mon, Jun 23, 2025 at 8:37 PM 7 replies 1,390 viewsPage 2 of 2
labquiet_amy
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Jun 24, 2025 at 5:35 PM#6

Adding the numbers, since they settle part of this. The four things to check on any report, in order: does it name your batch, who commissioned it, what method was used, and does it report content as well as purity. A report failing any of those is weak evidence regardless of the percentage on it.

Last edited: Jun 24, 2025 at 7:35 PM
32 2TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 29 others
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DeniseRN_TPA
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Tampa, FL
Jun 25, 2025 at 1:54 AM#7

One thing that is still open after NurseAsh_DET’s answer:

What a vetting checklist should actually contain, as opposed to a list of things that are easy to fake?

31 1hyun_seoul, jim_asheville, matt_MKE and 28 others
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SarahChen_PharmD
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Jun 25, 2025 at 10:13 AM#8
labquiet_amy said:
The four things to check on any report, in order: does it name your batch, who commissioned it, what method was used, and does it report content as…

There is a second half to this that has not been said yet. The provenance questions are more useful than the numbers. Does the report name the batch on your vial. Is the date consistent with when that batch existed. Is it addressed to the vendor or to the person who paid for the test. Was the sample taken from general stock or supplied by the vendor. A perfect certificate for a different batch is worth nothing, and vendor-supplied samples are the most common way a genuine report ends up misleading.

30 0paul_denver, TinaHashiRN, robert_kc and 27 others
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pam_columbus
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Columbus, OH
Jun 25, 2025 at 6:32 PM#9

Reporting back.

Went back through my own correspondence with an earlier supplier and the warning signs were all there in the replies, weeks before the quality changed. I was reading the product and not the behaviour.

29 24tammy_FL, Dr.LipidDallas, alex_tucson and 26 others
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ChrisMacros
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Jun 27, 2025 at 10:26 AM#10
SarahChen_PharmD said:
The provenance questions are more useful than the numbers.

Right, and one flattering data point from a group buy is not consistency. Consistency means separate batches, separately commissioned, over months.

Last edited: Jun 27, 2025 at 1:26 PM
31 4bri_stats, pete_manc_UK, anna.melb_AU and 28 others
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