VendorMark said:The mechanism and the magnitude are separate questions.
Adding the part of the answer the thread has not reached. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.
Following on from VendorMark — and this may be the naive question:
What did you change at the same time, and can you separate the two now?
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Browse GL BiochemDanielChem_CHI said:Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…
Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.
Happy to go further on any of that.
Reporting back.
Late follow-up. I did not do what was suggested, I did something adjacent, and it worked; posting the difference in case it matters to somebody.