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ForumsSide Effects & ManagementIs this normal?? My stomach is making SOUNDS — my results so far Page 2

Is this normal?? My stomach is making SOUNDS — my results so far

carl_compliance Wed, Oct 30, 2024 at 9:46 PM 38 replies 2,224 viewsPage 2 of 8
anders_CPH
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Oct 31, 2024 at 12:46 PM#6
JennaRN said:
Holding genuinely reduces total burden rather than redistributing it, because the gastric-emptying component adapts.

I dislike how confidently this board tells people to push through. Incidence figures around 20 to 25% at the higher doses are class-typical, but the trials also had a discontinuation column, and "manageable with protocols" is not the same as manageable for everyone.

41 11CryptoCarl, MariaRD, AussieAnna and 38 others
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TirzTom
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Oct 31, 2024 at 6:43 PM#7

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

40 10tom_AK, josh_phd_bmore, roxy_nash and 37 others
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sean_dublin
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Nov 1, 2024 at 12:40 AM#8
anders_CPH said:
I dislike how confidently this board tells people to push through.

There is a second half to this that has not been said yet. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

Last edited: Nov 1, 2024 at 1:40 AM
39 9gary_naperville, sean_dublin, hannah_MT and 36 others
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Dr.PathRoch
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Nov 1, 2024 at 6:36 AM#9

A narrower follow-up, since the general answer is now clear:

Whether holding at a lower dose for longer actually reduces total side-effect burden or just spreads it out?

38 8SaraMom3, Dr.MetabolicMD, RetaRick_CA and 35 others
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carl_compliance
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Nov 2024
Raleigh, NC
Nov 2, 2024 at 11:06 AM#10

Reporting back.

Holding the step for six weeks instead of four did it. Same dose, same food, and the nausea that had felt like a wall turned out to be a timing problem.

Last edited: Nov 2, 2024 at 2:06 PM
50 0dave_SLC, FDA_TrackerJim, ricardo_MIA and 47 others
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