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ForumsCOA & Analytical TestingLC-MS/MS vs HPLC for peptide analysis — November 2025 Page 6

LC-MS/MS vs HPLC for peptide analysis — November 2025

HealthEcon_DC Tue, Nov 18, 2025 at 8:01 PM 29 replies 1,356 viewsPage 6 of 6
TomTeleRx
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Delaware
Nov 23, 2025 at 4:52 AM#26
DoseLogDan said:
Practical: whatever you change, write down the date and the reason.

This is exactly what I could not find anywhere else.

26 24pete_manc_UK, anna.melb_AU, mark_tokyo and 23 others
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Dr.DermMIA
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Miami, FL
Nov 23, 2025 at 2:37 PM#27

From the other side of the consultation, briefly. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

Last edited: Nov 23, 2025 at 4:37 PM
27 0Dr.RenalNash, LipidDoc_ATL, BariatricNurseD and 24 others
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lisa_labSD
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Nov 24, 2025 at 12:22 AM#28
Dr.DermMIA said:
It helps to ask what evidence would change your mind before you look at any.

This matches mine closely enough to be worth saying so out loud. Nothing to add that would improve it.

28 1Dr.PulmRoch, maya_sedona, stefan_berlin and 25 others
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hank_denver
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Sep 2024
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Nov 24, 2025 at 10:07 AM#29
Dr.DermMIA said:
It helps to ask what evidence would change your mind before you look at any.

There is a second half to this that has not been said yet. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

Last edited: Nov 24, 2025 at 2:07 PM
29 2fiona_VT, denise_HTX, raj_cambridge and 26 others
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HealthEcon_DC
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Nov 24, 2025 at 7:52 PM#30

OP back with an update, since a thread like this is useless without one.

Late follow-up. I did not do what was suggested, I did something adjacent, and it worked; posting the difference in case it matters to somebody.

Last edited: Nov 24, 2025 at 9:52 PM
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