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ForumsMASH / Liver DiseaseAlcohol + MASH + GLP-1 — need advice Page 2

Alcohol + MASH + GLP-1 — need advice

sarah_nash92 Wed, Jun 26, 2024 at 11:40 AM 12 replies 1,927 viewsPage 2 of 3
Dr.GutHealth
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Jun 26, 2024 at 9:02 PM#6

One concrete data point for the thread. With resmetirom now available for MASH, combination approaches are being explored, so the standard of care in this area is moving faster than most threads assume.

31 1VanRx_Mike, steve_okc, dave_SLC and 28 others
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JakeBK_lifts
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Jun 27, 2024 at 12:43 AM#7

A narrower follow-up, since the general answer is now clear:

Whether normalised enzymes tell you anything about fibrosis, and what the right follow-up measurement is?

30 0JennaRN, LabKate, kate.chem and 27 others
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pat_auckland
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Jun 27, 2024 at 4:25 AM#8
Dr.GutHealth said:
With resmetirom now available for MASH, combination approaches are being explored, so the standard of care in this area is moving faster than most…

Adding the part of the answer the thread has not reached. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

29 24LarryQC_SD, wanda_boise, NurseAsh_DET and 26 others
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sarah_nash92
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Jun 27, 2024 at 8:07 AM#9

OP back with an update, since a thread like this is useless without one.

Coming back a few months on. It held. Nothing dramatic to report, which is the report.

Last edited: Jun 27, 2024 at 2:07 PM
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PharmacoVig_BOS
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Jun 28, 2024 at 1:51 AM#10
pat_auckland said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.

8 6LabKate, kate.chem, DataDave and 5 others
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