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ForumsExercise & Body CompositionMuscle protein synthesis window — September 2026 Page 3

Muscle protein synthesis window — September 2026

VanRx_Mike Sun, Aug 4, 2024 at 11:18 AM 11 replies 1,821 viewsPage 3 of 3
PharmacoVig_BOS
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Aug 4, 2024 at 8:52 PM#11
carl_compliance said:
There is also a quality change that the scan cannot see.

Right, and protein targets should be set on a reference weight rather than current weight. Setting 1.6 g/kg on a starting weight of 130kg produces a target nobody hits on a suppressed appetite.

That is the short version; the long version is somebody else's post.

33 6amsterdam_pete, LondonLisa, mike_nyc and 30 others
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NurseLeah_Nash
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Aug 5, 2024 at 12:31 AM#12
SkepticalSean said:
Agreed on the target, with the caveat that reference weight and current weight are different numbers.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Printing the relevant bit and taking it with me.

Last edited: Aug 5, 2024 at 1:31 AM
34 7BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 31 others
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nancy_portland
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Aug 5, 2024 at 4:09 AM#13
carl_compliance said:
There is also a quality change that the scan cannot see.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I think this board over-worries about lean mass. Some lean loss is obligatory — you need less muscle to move a smaller body, and preserving mass you no longer need is not a health outcome. The question is whether strength and function held, and mine did.

Happy to go further on any of that.

35 8MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 32 others
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stefan_berlin
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Aug 5, 2024 at 7:47 AM#14

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Worth separating that from lean-mass preservation, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Last edited: Aug 5, 2024 at 10:47 AM
36 9TirzTom, TrialTracker_MD, JennaRN and 33 others
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mike_mod
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Aug 5, 2024 at 11:25 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Carry on.

Last edited: Aug 5, 2024 at 1:25 PM
37 10PurityPaulOR, MaxMetOK, MounjBrad and 34 others
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